Pentalofos (Greek: Πεντάλοφος) is a village and a former community in Kozani regional unit, West Macedonia, Greece. Since the 2011 local government reform it is part of the municipality Voio, of which it is a municipal unit. It is located at 1060 meters elevation to the base of mountain Voio. The municipal unit has an area of 83.923 km, the community 38.113 km. The population of the municipal unit was 367 people, while the population of the community itself was 272 people as of 2021.