Phalombe is a district in the Southern Region of Malawi. The capital is Phalombe. The district covers an area of 1,394 km.² and has a population of 231,990.

At the time of the 2018 Census of Malawi, the distribution of the population of Phalombe District by ethnic group was as follows:

• 94.8% Lomwe
• 3.4% Nyanja
• 0.5% Chewa
• 0.4% Yao
• 0.3% Mang'anja
• 0.2% Ngoni
• 0.1% Tumbuka
• 0.1% Sena
• 0.1% Tonga
• 0.0% Nkhonde
• 0.0% Lambya
• 0.0% Sukwa
• 0.0% Others

There are five National Assembly constituencies in Phalombe:

• Phalombe - Central
• Phalombe - East
• Phalombe - North
• Phalombe - North East
• Phalombe - South

Since the 2009 election all of these constituencies have been held by members of the Democratic Progressive Party.

15°40′S 35°40′E / 15.667°S 35.667°E / -15.667; 35.667