Pittsboro Masonic Lodge, also known as Columbus Lodge No. 102, is a historic Masonic Lodge located at Pittsboro, Chatham County, North Carolina. It was built in 1838, and is a two-story, Greek Revival style frame building. In 1846, it was enlarged by the addition of the distinctive pedimented second-story overhang carried on heavy square pillars. It is one of the oldest still-functioning Masonic halls in North Carolina.

It was listed on the National Register of Historic Places in 1978.