Powell–McMullan House is a historic home located near Stanardsville, Greene County, Virginia. The original house was built about 1800 and expanded in 1842. It is a two-story, frame dwelling in a vernacular Greek Revival style. It has a metal-sheathed gable roof, exterior gable-end brick chimneys, and a one-story hipped roof front porch.

It was listed on the National Register of Historic Places in 2000.