Praha-Holešovice railway station (Czech: Nádraží Praha-Holešovice) is located in Holešovice, a northern district of Prague, capital city of the Czech Republic. Opened in 1985, the station was originally used as a terminus for international fast trains coming from the east. Since the completion of the Nové spojení ("new connection") in 2010, however, these trains terminate at the more central hub, Praha hlavní nádraží. Nevertheless, international trains from hlavní nádraží running north to Dresden and Berlin, as well as northwest-bound inter-regional trains still call here. The station is adjacent to Prague Metro's Nádraží Holešovice station on line C and also to stops of the same name on lines 6, 12, and 17 of the city's tramway system, as well as a bus station.

Preceding station		České dráhy		Following station
Praha hl.n. toward Vienna or Budapest		EuroCity trains		Ústí nad Labem hl.n. toward Berlin
Praha hl.n. Terminus		Regional fast trains		Ústí nad Labem hl.n. toward Cheb

Preceding station	European Sleeper			Following station
Praha hl.n. Terminus		Brussels - Prague		Ústí nad Labem towards Brussels-South

Preceding station	Esko Prague			Following station
Praha hl. n. Terminus		R4		Praha-Podbaba towards Děčín hl.n.
Praha-Libeň towards Praha-Hostivař		S41		Praha-Podbaba towards Roztoky u Prahy

50°06′37″N 14°26′23″E / 50.110278°N 14.439722°E / 50.110278; 14.439722