Prairie Street is one of four Metra railroad stations in Blue Island, Illinois along the Beverly Branch of the Rock Island District Line, and one of five total within the town of Blue Island. It is 15.8 miles (25.4 km) from LaSalle Street Station, the northern terminus of the line, and is both located on and named after Prairie Street. In Metra's zone-based fare system, Prairie Street is in zone 2. As of 2018, Prairie Street is the 220th busiest of Metra's 236 non-downtown stations, with an average of 30 weekday boardings.

As of 2022, Prairie Street is served as a flag stop by 40 trains (20 in each direction) on weekdays, by 21 trains (10 inbound, 11 outbound) on Saturdays, and by 16 trains (eight in each direction) on Sundays and holidays.

Parking is available on both sides of the tracks at a dead end at Prairie Street, south of the Burr Oak Avenue Bridge, which also crosses the main line and the freight yards between the two lines, the Burr Oak Yard on the north side of the bridge and the Iowa Interstate Railroad-Chicago Rail Link. Though a station house exists it contains no agent, and the station is a flag stop. No bus connections are available.

• Metra – Stations – Prairie Street station
• Station from Google Maps Street View