Prusie [ˈpruɕɛ] is a village in the administrative district of Gmina Horyniec-Zdrój, within Lubaczów County, Subcarpathian Voivodeship, in south-eastern Poland, close to the border with Ukraine. It lies approximately 32 kilometres (20 mi) east of Lubaczów and 112 km (70 mi) east of the regional capital Rzeszów.