Pumpkin Center is an unincorporated community in Okmulgee County, Oklahoma, United States. It is approximately 10 miles northeast of the city of Okmulgee, taking N 330 Rd. north off US Highway 62.

This is not to be confused with the Pumpkin Center located in Comanche County, Oklahoma which is about 10 miles east of Lawton, or with the Pumpkin Center located in Muskogee County, Oklahoma which is about 14 miles east of the city of Muskogee, or with the Pumpkin Center located in Cherokee County, Oklahoma, which is about 7.5 miles northeast of Braggs.

No information appears on the origins of the name; however, “Pumpkin Center” as a town name was widely publicized by one Cal Stewart, who was a popular spoken-word recording artist in the late 1890s and early 1900s. He frequently played the character of a gullible individual by the name of Uncle Josh Weathersby who hailed from the fictional town of "Pumpkin Center" or "Punkin Center". The recordings described life in Pumpkin Center, as well as the character’s collisions with modernity in New York City. Perhaps as a result, there are at least 31 communities in the U.S. named Pumpkin Center scattered across 16 states, including Alabama (3), Arizona (2), California (2), Florida, Georgia, Indiana (2), Kentucky, Louisiana, Maryland, Missouri (2), Mississippi, North Carolina (3), Oklahoma (4), South Dakota, Tennessee (3) and Virginia (2).