Pupėnai is a hamlet in Kėdainiai district municipality, in Kaunas County, in central Lithuania. According to the 2011 census, the hamlet has a population of 0 people. It was depopulated during the Soviet era land development programs (the 1970 census was the last with population being detected).

Historical population

Year Pop. ±% p.a. 1959 60 —     1970 56 −0.63% 1979 0 −100.00%	Year Pop. ±% p.a. 1989 0 0.00% 2001 0 0.00% 2011 0 0.00%
Source: 1902, 1923, 1959 & 1970, 1979, 1989, 2001, 2011