The Descalabrado River (Spanish: Río Descalabrado) is a river of Santa Isabel, Puerto Rico. It also goes through parts of Juana Díaz, and Coamo.

Poecilia sphenops, Guppy, and Awaous banana are some of the fish found in Descalabrado River.

See also

• List of rivers of Puerto Rico

17°58′53″N 66°27′05″W / 17.9813543°N 66.4512819°W / 17.9813543; -66.4512819