Radway Green & Barthomley railway station was built by the North Staffordshire Railway (NSR) and served the small Cheshire communities of Radway Green, Oakhanger and Barthomley. Located on the NSR line between Crewe and Kidsgrove it was the first station on the route from Crewe.

During the Second World War the station was the terminating point for many trains transporting workers to and from the nearby ROF Radway Green. This situation continued until a new station, Millway was built at the factory in 1942.