The Roman Catholic Diocese of Juigalpa (erected 21 July 1962, as the Territorial Prelature of Juigalpa) is a suffragan of the Archdiocese of Managua. It was elevated on 30 April 1991.

• Julián Luis Barni Spotti, O.F.M. (1962–1970), appointed Bishop of Matagalpa
• Pablo Antonio Vega Mantilla (1970–1993)
• Bernardo Hombach Lütkermeier (1995–2003), appointed Bishop of Granada
• Sócrates René Sándigo Jiron (2004–2019), appointed Bishop of León en Nicaragua
• Marcial Humberto Guzmán Saballo (2020–)

• Catholic Church in Nicaragua

• "Diocese of Juigalpa". Catholic-Hierarchy. Retrieved 2007-03-03.

12°06′23″N 85°21′52″W / 12.1064°N 85.3645°W / 12.1064; -85.3645