The Roman Catholic Archdiocese of Tuxtla (Latin: Archidioecesis Tuxtlensis) is a Metropolitan Archdiocese based in Tuxtla, Chiapas, Mexico. It is responsible for the suffragan dioceses of Tapachula and Las Casas. Pope Benedict XVI elevated it to the level of archdiocese on 25 November 2006.

In 2013, Pope Francis approved translations of the prayers for Mass and the celebration of sacraments into Tzotzil and Tzeltal. The translations include "the prayers used for Mass, marriage, baptisms, confirmations, confessions, ordinations and the anointing of the sick Bishop Arizmendi said Oct. 6 that the texts, which took approximately eight years to translate, would be used in his diocese and the neighboring Archdiocese of Tuxtla. Mass has been celebrated in the diocese in recent years with the assistance of translators—except during homilies—Bishop Arizmendi said in an article in the newspaper La Jornada.

• José Trinidad Sepúlveda Ruiz-Velasco (1965–1988), appointed Bishop of San Juan de los Lagos, Jalisco
• Felipe Aguirre Franco (1988–2000), appointed Coadjutor Archbishop of Acapulco, Guerrero
• José Luis Chávez Botello (2001–2003), appointed Archbishop of Antequera, Oaxaca
• Rogelio Cabrera López (2004–2012), appointed Archbishop of Monterrey, Nuevo León
• Fabio Martínez Castilla (2013–2023); formerly Bishop, Roman Catholic Diocese of Ciudad Lázaro Cárdenas

• Felipe Aguirre Franco (1974–1988), appointed Bishop here
• José Luis Mendoza Corzo (2007–

• Óscar Armando Campos Contreras, appointed Auxiliary Bishop of Antequera, Oaxaca in 2006
• José Alberto González Juárez, appointed Bishop of Tuxtepec, Oaxaca in 2015
• Guadalupe Antonio Ruíz Urquín, appointed Prelate of Huautla, Oaxaca in 2020

• List of Roman Catholic archdioceses in México

• www.arquidiocesisdetuxtla.blogspot.mx Official Blog at Blogger (in Spanish)

16°45′11″N 93°06′56″W / 16.7531°N 93.1155°W / 16.7531; -93.1155