Route 146 is a 16.24-mile (26.14 km) north-south state highway in the U.S. state of Rhode Island, maintained by the Rhode Island Department of Transportation (RIDOT). Spanning approximately 16 miles (26 km) along a northwest–southeast axis, it links the cities of Providence, Woonsocket, and Worcester, Massachusetts.

The southern terminus of Route 146 is located at Interstate 95 (I-95) in Providence. The majority of the route is a freeway, with the exception of at-grade crossings and driveway access in the towns of North Smithfield and Lincoln. The northern terminus is located at the Rhode Island–Massachusetts state line in Millville, where it transitions into Massachusetts Route 146 and continues northbound towards the Massachusetts Turnpike in Millbury and I-290 in Worcester.

Route 146 begins in downtown Providence at I-95 northbound exit 38 (there is no direct access from I-95 southbound; access to Route 146 is via surface streets). Locally it is known as Old Louisquisset Pike, and is a narrow four-lane freeway with no shoulders and a simple Jersey barrier median separating oncoming traffic. The first two interchanges are partial access only, with Route 7 (Douglas Avenue) and Route 246 (Charles Street) and provide access between Route 146 and I-95 via surface streets for where there is no direct access (southbound I-95 to northbound Route 146, and southbound Route 146 to northbound I-95). The first complete interchange is a diamond interchange with Branch Avenue, followed by a partial interchange with Route 15 (no northbound entrance to Route 146). The next interchange, with Route 246 a second time, provides the access missing from the Route 15 interchange.

At this point, now in North Providence the "Old Louisquisset Pike" designation leaves to follow Route 246, and the Route 146 freeway becomes the Eddie Dowling Highway. Near the southern boundary of Lincoln, there is a southbound-only offramp (no other access) with Route 246, while the northbound side abuts Olney Pond in the Lincoln Woods State Park. Two partial cloverleaf interchanges follow with Twin River Road and Route 123/Breakneck Hill Road. The next interchange northbound is a right-in/right-out terminus of Sherman Avenue, while southbound has access to Route 246 here. A single onramp provides Wilbur Road an entrance to northbound Route 146 next, then a modified cloverleaf interchange with Route 116, followed shortly by a full cloverleaf interchange with I-295 and the southern terminus of Route 99, which is a short connector freeway to the city of Woonsocket. Route 99 access is a northbound exit/southbound entrance only, the other directions need to use surface streets for access.

North of this interchange, the road turns into an arterial road with at-grade crossings and driveway access through the southern part of the town of North Smithfield, Rhode Island. A stoplight marks the only major intersection, an at-grade crossing with Sayles Hill Road, which doubles back and has a right in/right out interchange with southbound Route 146. At the partial interchange with Route 146A (northbound exit and southbound entrance) the freeway resumes, now called the North Smithfield Expressway, which has three interchanges in the town: Route 104, Pound Hill Road, and a complex interchange with School Street and Route 146A that also provides access to Route 5 and Route 102. Approximately two miles (3.2 km) north of this interchange, the freeway continues into Massachusetts as Massachusetts Route 146, the Worcester–Providence Pike.

This section needs expansion. You can help by adding to it. (June 2012)

Prior to the construction of the two freeway sections, Route 146 used present-day Route 246 and Route 146A. The only part of the original alignment still in use is the non-freeway section between I-295/Route 99 and Route 146A in the southern part of North Smithfield.

In May 2019, Route 146 received mile-based exit numbers. Previously, the exits were unnumbered.

In May 2019, the Rhode Island Senate announced that the state would borrow $200 million to reconfigure I-95 through Downtown Providence, near the southern terminus of Route 146. The replacement of the Providence Viaduct with twin bridges is intended to alleviate the bottleneck created by traffic entering I-95 from US Route 6 (US 6) and Route 10, and exiting towards Route 146 and US 44. The project is expected to cost $250 million.

In 2022, RIDOT began work on an overpass at Sayles Hill Road, the only set of traffic signals along the route in Rhode Island. The project also includes constructing service roads and bus bays, and rebuilding the interchange with Route 146A at North Smithfield. Work is scheduled to be completed in 2026.

RIDOT erected two toll gantries in 2019, one in Lincoln and one in North Smithfield, for truck-only electronic toll collection. Those gantries have been shut off since September 2022.

The entire route is in Providence County.

Location	mi	km	Exit	Destinations	Notes
Providence	0.00	0.00	–	I-95 south to I-195 east / US 6 / Route 10 south – Downtown ProvidenceModule:Jct error: Invalid "to" argument	Southern terminus; exit 38 on I-95
	0.30	0.48	1A	Route 246 (Charles Street) / Admiral Street – State Offices	Southbound exit and northbound entrance
	1.40	2.25	1B	Branch Avenue	Signed as exit 1 northbound
North Providence	2.50	4.02	2	Route 15 (Mineral Spring Avenue) – North Providence, Pawtucket	No northbound entrance
Lincoln	4.00	6.44	4A	Route 246 (Old Louisquisset Pike)	Southbound exit only
	4.50	7.24	4B	Twin River Road	Signed as exit 4 northbound
	5.00	8.05	5	Route 123 (Breakneck Hill Road)
	6.40	10.30	6	Route 246 (Old Louisquisset Pike) / Sherman Avenue	Signed for Route 246 southbound, Sherman Avenue northbound
	7.40	11.91	7	Route 116 – Lincoln, Smithfield	Southbound exit 7 provides access to Route 246 via collector–distributor lanes shared with exits 8A-B
	8.50	13.68	8	I-295 – Boston Ma, Warwick	Signed as exits 8A (north) and 8B (south); exits 18A-B on I-295
	8.80	14.16	8C	Route 99 north to Route 122 – Woonsocket, Cumberland	Northbound exit and southbound entrance; accessed from the collector–distributor lanes shared with exits 8A-B
	9.00	14.48	9	Reservoir Road	Interchange; no northbound exit
			Northern end of freeway section
	9.70	15.61		To Route 99 north	Access via Sayles Hill Road; currently being reconfigured into an interchange as part of a project to complete the freeway gap in North Smithfield
North Smithfield	10.50	16.90	Southern end of freeway section
			–	Sayles Hill Road	Southbound exit and entrance; will be reconfigured as part of a project to complete the freeway gap in North Smithfield
	10.60	17.06	10	Route 146A north – Woonsocket, Park Square	Southbound access is via center median u-turn ramp; exit number not signed southbound; southern terminus of Route 146A; will be reconfigured as part of a project to complete the freeway gap in North Smithfield
	12.10	19.47	11	Route 104 – Woonsocket, North Smithfield
	13.40	21.57	13	Pound Hill Road – North Smithfield	Access to Industrial Drive and CVS Distribution Center
	14.30	23.01	14	Route 146A – North Smithfield, Burrillville
	16.24	26.14	–	Route 146 north – Worcester	Continuation into Massachusetts
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Incomplete access

Route 146A
Location	North Smithfield–Woonsocket-Burrillville
Length	5.9 mi (9.5 km)

Route 146A is a numbered state highway running 5.9 miles (9.5 km) in Rhode Island. It was designated as Route 146 before the construction of the North Smithfield Expressway. The road follows a former stagecoach path through historic Union Village in North Smithfield. This road was known as "the Great Road". The northern end of the road crosses the state line near Buxton Street at Uxbridge, Massachusetts. This section was known as Ironstone, after good quality bog iron ore found near here.

It runs for 5.9 miles (9.5 km) through North Smithfield on Route 146 to Massachusetts state line at Route 146A using Eddie Dowling Highway, Smithfield Road, Great Road, Victory Highway, North Main Street and Quaker Highway.

Major intersections
The entire route is in Providence County.

Location	mi	km	Destinations	Notes
North Smithfield	0.0	0.0	Route 146 – Providence, Worcester, MA	Southern terminus; exit 10 on Route 146
Woonsocket	1.6	2.6	Route 104 (Greenville Road)
North Smithfield	3.9	6.3	Route 146 – Providence, Worcester, MA	Exit 14 on Route 146
Burrillville	5.2	8.4	Route 5 south (Victory Highway) / Route 102 south (North Main Street)	Southern terminus of concurrency with Route 5; northern terminus of Route 102
	5.3	8.5	Route 5 north (Central Street)	Northern terminus of concurrency with Route 5
	5.9	9.5	Route 146A north – Uxbridge	Continuation into Massachusetts
1.000 mi = 1.609 km; 1.000 km = 0.621 mi       Concurrency terminus

• U.S. Roads portal

• 2019 Highway Map, Rhode Island