The Route des Grands Crus (French pronunciation: [ʁut de ɡʁɑ̃ kʁy]; roughly, "road of the great wines") is the name of a tourist route situated in Burgundy, France.

The approximately 60-kilometre route runs along the foot of the Côte d'Or escarpment, from Dijon in the north to Santenay in the south. Thus it runs through many of the great appellations of Burgundy wine, hence the name of the route. It takes the visitor through the vineyards of the Côte de Nuits and the Côte de Beaune and the back hills (Hautes-Côtes) behind and above the wine slopes.

It is punctuated by 33 villages or little towns, including Beaune, many of which have picturesque churches.

From north to south:

• Marsannay-la-Côte
• Côte de Nuits
  • Fixin
  • Gevrey-Chambertin
  • Morey-Saint-Denis
  • Chambolle-Musigny
  • Vougeot
  • Flagey-Echézeaux
  • Vosne-Romanée
  • Nuits-Saint-Georges
• Côte de Beaune
  • Aloxe-Corton
  • Savigny-Lès-Beaune
  • Beaune
  • Pommard
  • Volnay
  • Meursault

• French wine
• Burgundy wine
• Côte de Nuits
• Saisy

• Coates, Clive (1997). Côte D'Or: A Celebration of the Great Wines of Burgundy. Weidenfeld Nicolson. ISBN 0-297-83607-2.
• Nanson, Bill (2012). The Finest Wines of Burgundy: A Guide to the Best Producers of the Côte d'Or and Their Wines (Fine Wine Editions Ltd). Aurum Press. p. 320. ISBN 978-1-84513-692-5. An inexpensive introduction to the Côte d'Or and currently the most up to date book.

• Description
• thewinedoctor.com Archived 2013-03-29 at the Wayback Machine An overview of the geography and wines of Burgundy
• The Burgundy Report Good descriptions of the vineyards and vintages.

47°4′4.8″N 4°52′15.6″E / 47.068000°N 4.871000°E / 47.068000; 4.871000