Ruffré-Mendola (Rufré-Méndola in local dialect) is a comune (municipality) in Trentino in the northern Italian region Trentino-Alto Adige/Südtirol, located about 40 kilometres (25 mi) north of Trento. As of 31 December 2004, it had a population of 444 and an area of 6.6 square kilometres (2.5 sq mi).

It borders the following municipalities: Sarnonico, Caldaro and Cavareno.

Demographic evolution