Sahatsakhan (Thai: สหัสขันธ์, pronounced [sā.hàt.sā.kʰǎn]) is a district (amphoe) in the central part of Kalasin province, northeastern Thailand.

Neighboring districts are (from the east clockwise): Somdet, Mueang Kalasin, Nong Kung Si, Sam Chai, and Kham Muang of Kalasin Province.

The district is divided into eight sub-districts (tambons), which are further subdivided into 85 villages (mubans). Non Buri is a township (thesaban tambon) which covers parts of tambon Non Buri. There are a further seven tambon administrative organizations (TAO).

No.	Name	Thai name	Villages	Pop.
1.	Phu Sing	ภูสิงห์	9	2,593
2.	Sahatsakhan	สหัสขันธ์	13	6,432
3.	Na Makhuea	นามะเขือ	12	7,572
4.	Non Sila	โนนศิลา	13	8,051
5.	Nikhom	นิคม	7	3,020
6.	Non Laem Thong	โนนแหลมทอง	12	5,291
7.	Non Buri	โนนบุรี	11	5,351
8.	Non Nam Kliang	โนนน้ำเกลี้ยง	8	3,226