Saint-Ambroix (French pronunciation: [sɛ̃.t‿ɑ̃bʁwa]) is a commune in the Cher department in the Centre-Val de Loire region of France.

A farming area comprising the village and two hamlets situated by the banks of the river Arnon, some 17 miles (27 km) southwest of Bourges, at the junction of the D18, D84 and the D99e roads. The commune borders the department of Indre.

Historical population

Year	Pop.	±%
1962	468	—
1968	496	+6.0%
1975	409	−17.5%
1982	406	−0.7%
1990	386	−4.9%
1999	374	−3.1%
2008	395	+5.6%

• The church, dating from the twelfth century.
• A fifteenth-century manorhouse.
• Considerable Roman remains: a graveyard and artefacts.
• The remains of the priory of Semur.

• Communes of the Cher department