Saint-Mesmin (French pronunciation: [sɛ̃ mɛmɛ̃]; Limousin: Sent Maimin) is a commune in the Dordogne department in Nouvelle-Aquitaine in southwestern France.

The commune is located in the north-east corner of the Dordogne department, on a hill above the river Auvézère. The village is located 42 km (26 mi) north-east of Périgueux. The area consists of forests and farmland.

From the creation of the departments in 1790 Saint-Mesmin was first included in the Corrèze department. Three years later in 1793 it joined the Dordogne department.

Historical population

Year	Pop.	±% p.a.
1968	534	—
1975	455	−2.26%
1982	393	−2.07%
1990	324	−2.38%
1999	284	−1.45%
2009	264	−0.73%
2014	311	+3.33%
2020	326	+0.79%
Source: INSEE

The largest population that the census recorded was 1,168 in 1886. Since World War I, the population has gradually been declining until it reached its lowest point in 2009.

• The Auvézère has eroded a more than 100 meter deep gorge in limestone rock. There are footpaths through the gorge, offering access to the cascades.
• The Puy des Ages is a 1.5 km (0.93 mi) long rocky ridge on the border of the communes of Saint-Cyr-les-Champagnes and St-Mesmin. Its maximum elevation is 415 m above sea level.

• Communes of the Dordogne department

• Official site
• Moulin-Mesmin site