Saint-Nicolas (French pronunciation: [sɛ̃ nikɔla]) is a district within Les Chutes-de-la-Chaudière-Ouest borough of the city of Lévis, Quebec, Canada on the St. Lawrence River. Prior to 2002, it was an independent municipality.

The history of Saint-Nicolas goes back to 1694. It is one of the oldest parishes in Canada. Its heritage is a testimony to its long history.

The city was named in honour of Saint Nicolas de Myre.

In 2002, following many merges with other municipalities, Saint-Nicolas was one of nine cities merged with Lévis.

According to the Canada 2006 Census:

• Population: 18,437
• % Change (2001–2006): +10.8
• Dwellings: 7,024
• Area (km): 95.09 km
• Density (persons per km): 193.9

46°42′N 71°24′W / 46.700°N 71.400°W / 46.700; -71.400 (Saint-Nicolas, Quebec)