Saint Thomas Aquinas Regional Catholic High School is a private, Roman Catholic high school in unincorporated Tangipahoa Parish, Louisiana, near Hammond. It is located in the Roman Catholic Diocese of Baton Rouge.

The school began operations in August 1986 with 35 students.

The school offers grades 9, 10, 11, and 12. In the 2019–2020 school year, the student body was distributed as shown:

Grade	Students
9	95
10	72
11	89
12	58

This school has about 314 students. Of these, 271 are categorized as "white, non-Hispanic." The school is about 86% white.

Saint Thomas Aquinas Regional Catholic athletics competes in the LHSAA.

• Modestas Bukauskas, known as the "Baltic Gladiator" (born February 10, 1994), is a Lithuanian-British mixed martial artist who competes in the light heavyweight division of the Ultimate Fighting Championship (class of 2012).
• Cameron Dantzler NFL player, played cornerback for the Minnesota Vikings

• School Website