The Samuel Cox House is a historic house located near Scottville, Ashe County, North Carolina. It is a "T"-plan dwelling consisting of a two-story log, gable roof, main section built in the mid-19th century, with a later one-story frame ell and frame addition on the east side of the ell. The log section was covered with weatherboards about 1880. The front facade features a one-story, full-width shed-roof porch.

It was listed on the National Register of Historic Places on November 7, 1976.