The Port of San Juan (Spanish: Puerto de San Juan) is a large seaport facility in and around San Juan Bay in Puerto Rico. Primarily located within the capital municipality of San Juan, the Port of San Juan consists of multiple public and private passenger and cargo facilities. Public facilities are administered by the Puerto Rico Ports Authority (PRPA), under the Department of Transportation and Public Works of Puerto Rico.

The cruise area of the port, known as the San Juan Cruise Port, is located in and around Caño de San Antonio (San Antonio Canal), a narrow navigable section of San Juan Bay situated between Old San Juan in San Juan Islet and the Puerto Rico Convention Center and Fernando Luis Ribas Dominicci Airport in the subbarrio of Isla Grande in the barrio of Santurce in San Juan. The cruise port consists of piers 1, 3, 4, 11 to 14, as well as the Pan American piers I and II.

The main cargo facilities of the port are located in the Puerto Nuevo Terminal in the barrios of Hato Rey Norte and Gobernador Piñero in San Juan. It handles containerized and break-bulk cargoes with and without shore-side cranes. Containers are also handled at the public Army Terminal in the barrio of Pueblo Viejo in Guaynabo and the private barge Isla Grande Terminal in the subbarrio of Isla Grande in the barrio of Santurce in San Juan. Additional private facilities handle containers in ro-ro and barge service, and bulk commodities. Major commodities handled at the port include manufactured products, distillate fuel oil, gasoline, foodstuffs, and kerosene.

The Port of San Juan's cargo facilities are located on the southern portion of San Juan Bay. Of the approximately eight cargo terminals, five are located in the Puerto Nuevo district of San Juan and the other three are located in the neighboring municipality of Guaynabo. The cargo facilities allow for more than 500,000 square feet (46,000 m) of space for loading and unloading cargo.

The location of the port's cargo facilities give it immediate access to Puerto Rico's vast expressway system and several major local routes, this allows for the fast and efficient transportation of goods throughout the Metropolitan Area and the rest of the island.

The Port of San Juan's passenger facilities are located along San Antonio Canal. Of the 15 piers in the channel, four accommodate cruise ships while others serve cargo vessels and the Cataño Ferry.

The Cataño Ferry (Lancha de Cataño) provides multiple daily round-trips from San Juan to Cataño.

While most cargo ships dock on the south side of the bay, cruise ships arrive at one of the four cruise piers located along San Antonio Canal. This arrangement allows tourists to walk to major attractions such as Old San Juan and the Puerto Rico Convention Center District. The short distance between the Luis Muñoz Marín International Airport and the cruise ship docks is 7 miles and makes the area a prime location for cruise companies. Cruise ship companies, such as Carnival Cruises and Royal Caribbean prefer this setting, and have made the San Juan one of their ports of call. Some of the most recognized ships to have docked at the Port of San Juan during the late 1970s and early 1980s, were the Carla C, and Cunard's Countess and Princess ships.

The following cruise ships are homeported at San Juan:

• Brilliance of the Seas (seasonal)
• Celebrity Summit (seasonal)
• Disney Magic
• Grand Princess
• Jewel of the Seas (seasonal)
• Norwegian Epic
• Norwegian Viva
• Rhapsody of the Seas
• Silver Wind (seasonal) depart from San Juan to Fort Lauderdale
• Sea Dream II (seasonal)

• Star Pride
• Viking Sea

The following operators visit San Juan:

• AIDA Cruises
• Azamara Club Cruises
• Carnival
• Celebrity
• Costa Crociere
• Crystal Cruises
• Disney Cruise Line
• Holland America Line
• MSC Cruises
• Norwegian Cruise Line
• Oceania Cruises
• Princess Cruises
• Regent Seven Seas Cruises
• Royal Caribbean
• SeaDream Yacht Club
• Silversea
• Viking Ocean Cruises
• Windstar Cruises

The following is a listing of the majority of the locations served by passenger ship and ferry routes.

After Hurricane Maria devastated the communications and electricity network in Puerto Rico on September 20, 2017, the Port could not get enough truck drivers to distribute containers of relief supplies. The landslides, floods, lack of gasoline, water and food, caused a "vast humanitarian and logistical challenge" and a FEMA rep said on October 3, "We are currently developing a strategy to reach the center of the island.”

• Transportation in Puerto Rico
• Port of Mayagüez
• Port of Ponce

• Puerto Rico Port Authority's page (in Spanish)
• Estuario de la Bahia de San Juan (in Spanish)
• Norwegian Cruises to San Juan

18°27′44″N 66°06′43″W / 18.4622°N 66.1120°W / 18.4622; -66.1120