San Luis, officially the Municipality of San Luis (Kapampangan: Balen ning San Luis; Tagalog: Bayan ng San Luis), is a municipality in the province of Pampanga, Philippines. According to the 2020 census, it had a population of 58,551 people.

San Luis is politically subdivided into 17 barangays. Each barangay consists of puroks and some have sitios.

Population census of San Luis

Year Pop. ±% p.a. 1903 10,067 —     1918 9,830 −0.16% 1939 10,966 +0.52% 1948 9,472 −1.61% 1960 14,873 +3.83% 1970 20,205 +3.11% 1975 23,866 +3.40% 1980 25,701 +1.49%	Year Pop. ±% p.a. 1990 31,920 +2.19% 1995 36,005 +2.28% 2000 41,554 +3.12% 2007 47,517 +1.87% 2010 49,311 +1.36% 2015 54,106 +1.78% 2020 58,551 +1.56%
Source: Philippine Statistics Authority

In the 2020 census, the population of San Luis, Pampanga, was 58,551 people, with a density of 1,000 inhabitants per square kilometre or 2,600 inhabitants per square mile.

Like other municipalities and cities in Pampanga, its people are mostly Kapampangan.

Roman Catholicism remains the predominant faith of the townsfolk. Other Christian denominations, such as Iglesia ni Cristo, the United Methodist Church, Members Church of God International, Evangelicals, Ang Iglesia Metodista sa Pilipinas, Baptists, and Born Again Christianity can be found in the municipality.

Poverty incidence of San Luis

5 10 15 20 25 30 2006 20.30 2009 16.20 2012 6.02 2015 9.61 2018 6.01 2021 11.86 Source: Philippine Statistics Authority

Transportation, trade and commerce in San Luis is concentrated at the town center where the public market, cockpit, municipal hall, church, schools, hospital, clinics, and commercial spaces are situated.

The municipal government is divided into three branches: executive, legislative and judiciary. The judicial branch is administered solely by the Supreme Court of the Philippines. The executive branch is composed of the mayor and the barangay captains for the barangays. The legislative branch is composed of the Sangguniang Bayan (town assembly), Sangguniang Barangay (barangay council), and the Sangguniang Kabataan for the youth sector.

The current mayor of San Luis, Dr. Jayson S. Sagum or also known as Dr. J, and the vice mayor is Mon A. Sagum

Its façade can compare immeasurably with existing Spanish-style church edifices and architectural design. The church is located in a place that used to be called Cabagsac, referring to the proliferation of fruit bats. In fact, today, a fishnet is permanently installed high above the altar precisely to catch thousands of bats that are roosting inside the church. The interior is dark, has an ambience of antiquity and mystery and overpowering odor of bat urine. The main attraction is the three-tower facade, perhaps one of its kind in the country. Not to be missed is the ancient cemetery located in a hidden corner at the back of the church, with some tombstones dating back to the 1800s and bearing the names of the town's prominent families, including the Elizaldes, Ablazos, Francos, Tarucs, among others.

There is a prime school in the town aside from public elementary and high schools.

• Luis Taruc (June 21, 1913 – May 4, 2005), founder and leader of Hukbalahap, was born of peasant folks in the farming town of San Luis, Pampanga.

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  Rice Field in San Jose, San Luis
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  Downtown San Luis
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  Municipal Hall of San Luis
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  Public market
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  District Hospital

• San Luis Profile at PhilAtlas.com
• Philippine Standard Geographic Code
• Philippine Census Information
• Local Governance Performance Management System