San Piero a Sieve is a frazione of the comune (municipality) of Scarperia e San Piero, located in the Metropolitan City of Florence, in Tuscany, Italy, about 20 kilometres (12 mi) north of Florence. It was an independent comune until 1 January 2014.

• Pieve of San Pietro. It houses a baptismal font from the house of Giovanni della Robbia (c. 1508)
• Church of San Niccolò a Spugnole
• Medici fortress of San Martino
• Convent of Bosco ai Frati

The Medici Villa del Trebbio is located within the territory of San Piero.

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