Sans Souci Girls' High School is a Public English medium high school for girls situated in the suburb of Newlands in Cape Town in the Western Cape province of South Africa. The school was established in 1960 and was decreed by the apartheid-era South African government as whites only school. In 1991 the school opened enrollment to all races as a model B school.

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List of headmistresses at Sans Souci Girls' High School.

• Joan Kenyon (1960–1978)
• Fiona Watson (1978–1997)
• Elizabeth Fugard (1997–1999)
• Charmaine Murray (1999–2017)
• Ruschida O'Shea (2017–present)

One of the school's former teachers, Denise Frick, is a South African chess master and winner of the 2015 South African Woman's Closed Chess Championships.

• Archery
• Athletics
• Chess
• Cricket
• Cross country
• Cycling
• Diving
• Equestrian
• Hockey
• Netball
• Rowing
• Squash
• Swimming
• Table tennis
• Tennis
• Water polo

In 2016 the school's hair and language policies caused controversy resulting in a broader national discussion of exclusionary or discriminatory school policies and an investigation by the Western Cape Education Department.

In 2019 a teacher at the school was filmed slapping a student. The incident resulted in an Equity Court case against the teacher that was ultimately withdrawn.

• Claire Mawisa - TV & radio presenter

• Official website

• South African College Schools Website
• SACS Junior School
• SACS Rugby Site

33°58′34″S 18°27′45″E / 33.9761°S 18.4625°E / -33.9761; 18.4625