The church of Sant'Aponal is a deconsecrated Roman Catholic church in the sestiere of San Polo in Venice, Italy.

The church was founded in the 11th century, by refugees from Ravenna and dedicated to Apollinaris of Ravenna. Restored over the centuries, it underwent major reconstruction in the 15th century. During the Napoleonic occupation, it was deconsecrated and only reconsecrated in 1851. For a time it was used as a prison for political prisoners. It was re-closed in 1984, and is now mainly an archive. The facade retains bits of Gothic architecture decoration.

• Patriarch of Venice, entry on church
• Guide d'Italia (serie Guide Rosse) - Venezia - Touring Club Italiano - pagg. 384-385 ISBN 978-88-365-4347-2