Santhià railway station is the main station serving the comune of Santhià, in the Piedmont region, northwestern Italy. It is the junction of the Turin–Milan, Santhià–Biella and Santhià–Arona railways.

The station is currently managed by Rete Ferroviaria Italiana (RFI). Train services are operated by Trenitalia. Each of these companies is a subsidiary of Ferrovie dello Stato (FS), Italy's state-owned rail company.

The station was opened from 1856, with Turin–Milan railway.

Five tracks of which are equipped with platforms, pass through the station.

The station is served by the following services:

• Express services (Regionale Veloce) Turin - Chivasso – Santhià – Vercelli – Novara – Milan
• Regional services (Treno regionale) Turin - Chivasso - Santhià - Biella
• Regional services (Treno regionale) Chivasso - Santhià - Vercelli - Novara
• Regional services (Treno regionale) Santhià - Biella San Paolo

Preceding station		Trenitalia		Following station
Chivasso toward Torino Porta Nuova		Treno regionale		Vercelli toward Milano Centrale
Chivasso toward Torino Lingotto		Treno regionale		Biella San Paolo Terminus
Tronzano toward Chivasso		Treno regionale		San Germano Vercellese toward Novara
Terminus		Treno regionale		Salussola toward Biella San Paolo

Since 17 June 2012 the train service to Arona has been suspended and replaced by a bus service.

• History of rail transport in Italy
• List of railway stations in Piedmont
• Rail transport in Italy
• Railway stations in Italy

Media related to Santhià railway station at Wikimedia Commons