Santoche (French pronunciation: [sɑ̃tɔʃ]) is a former commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France. On 1 January 2017, it was merged into the new commune Pays-de-Clerval.

Santoche lies 2 km (1.2 mi) north of Clerval in the valley of the Doubs on an ancient Roman road.

The commune has the only dolmen in the department and a rectangular mound surrounded by ditches called the Motte Jules César, which was once a Gallic temple.

Archaeological digs have discovered prehistoric objects and bones.

Historical population

Year	Pop.	±%
1962	31	—
1968	35	+12.9%
1975	51	+45.7%
1982	74	+45.1%
1990	77	+4.1%
1999	68	−11.7%
2008	81	+19.1%
2012	80	−1.2%

• Communes of the Doubs department

• Santoche on the regional Web site (in French)