The second presidency of Donald Trump is set to begin on January 20, 2025, when Trump will be inaugurated as the 47th president of the United States. Trump, who previously served as the 45th president from 2017 to 2021, is scheduled to take office following his victory over Democratic incumbent Vice President Kamala Harris in the 2024 presidential election, winning both the popular and the electoral college vote. Upon taking office, he will become the second president in U.S. history to serve non-consecutive terms after Grover Cleveland in 1893, the oldest individual to assume the presidency, the first to take office after having been impeached, and the first convicted felon to take office.

Donald Trump officially announced his candidacy for the nomination of the Republican Party in the 2024 presidential election on November 15, 2022, at his Mar-a-Lago residence in a roughly hour-long speech. In March 2024, Trump clinched the nomination by winning a majority of the delegates to become the presumptive nominee for the Republican Party following the party's presidential primaries. Trump selected Senator JD Vance of Ohio, a former critic of his, as his running mate, and the two were officially nominated as the Republican ticket at the 2024 Republican National Convention.

Incumbent president Joe Biden initially ran for re-election for the Democratic nomination, becoming the party's presumptive nominee in March 2024 after comfortably winning the primaries with little opposition. However, following a widely panned debate performance and amid increasing concerns about his age and health, Biden officially withdrew from the race in July 2024. Biden endorsed Kamala Harris, his 2020 running mate and vice president of the United States, as his successor, who announced her campaign on July 21. The following day, Harris received enough non-binding delegates to become the party's new presumptive nominee; at the Democratic National Convention in August 2024, she formally accepted the party's nomination with Governor Tim Walz of Minnesota as her running mate.

On November 6, 2024, the day after the election, Trump was confirmed to have won Wisconsin (a flip from the previous presidential election), thereby receiving enough electoral votes to secure the presidency. The electoral votes will be certified on January 6, 2025. Trump, upon taking office, will be the second president in U.S. history to serve non-consecutive terms after Grover Cleveland in 1893, the oldest individual to assume the presidency, and the first convicted felon to serve the presidency following his conviction in May 2024. Vance, as one of the youngest vice presidents in U.S. history, will be the first Millennial vice president; additionally, he will be the first vice president to have served in the Marine Corps. In the concurrent congressional elections, Republicans maintained their majority in the House of Representatives and won control of the Senate.

In August 2024, Trump began forming a transition team led by Linda McMahon and Howard Lutnick. According to The New York Times, Trump is "superstitious" and prefers to avoid discussing the presidential transition process until after Election Day. His transition team is expected to rely on the work of the America First Policy Institute, rather than The Heritage Foundation, a conservative think tank that garnered controversy during the election for Project 2025, a set of initiatives that would reshape the federal government. By October, he had not participated in the federal presidential transition process, and he has not signed a required ethics pledge, as of November.

Trump is expected to be inaugurated at the United States Capitol on January 20, 2025.

On November 11, 2024, The New York Times reported that U.S. Senator Marco Rubio of Florida was expected to be Trump's Secretary of State; he was officially named on November 13. It had been reported on November 8 that congressman Mike Rogers was being considered for Secretary of Defense, but on November 12 Trump announced that military veteran and Fox News host Pete Hegseth would be his nominee for the position. That same day, CNN reported that South Dakota governor Kristi Noem would be named as Secretary of Homeland Security, which Trump later confirmed. On November 13, Trump selected representative Matt Gaetz for Attorney General. The following day, environmental lawyer and activist Robert F. Kennedy Jr. was selected as the Secretary of Health and Human Services. On November 15, North Dakota Governor Doug Burgum was the expected nominee for Secretary of the Interior. Former representative and Air Force reservist Doug Collins was selected for Secretary of Veterans Affairs that day.

Trump has proposed multiple candidates for several Cabinet positions, including Scott Bessent for Secretary of the Treasury. Potential contenders for the post of Secretary of Energy include first-term Secretary Dan Brouillette and former lower-level Department of Energy staffers Mark Menezes, Paul Dabbar, and Daniel Simmons, and contenders for Secretary of Agriculture include undersecretary Ted McKinney, Texas Agriculture Commissioner Sid Miller, and former ambassador to the FAO Kip E. Tom.

On November 7, Trump selected Susie Wiles, a co-chair of his presidential campaign, as his Chief of Staff. She will be the first woman to hold the position. Three days later, CNN reported that Trump had offered representative Elise Stefanik the position of ambassador to the United Nations. The following day, The Wall Street Journal reported that representative Michael Waltz will serve as his National Security Advisor, former representative Lee Zeldin was announced as Trump's nominee for administrator of the Environmental Protection Agency, and former representative Tulsi Gabbard for Director of National Intelligence.

Several individuals have declined to serve in Trump's administration or have been excluded from serving. On October 29, U.S. Senator Cynthia Lummis of Wyoming declined to be considered for Secretary of the Interior. On November 7, U.S. Senator Tom Cotton of Arkansas declined to serve in an administration role. On November 9, Trump said that he would not re-invite Nikki Haley or Mike Pompeo, his Ambassador to the United Nations and Secretary of State, respectively, from his first administration. On November 11, Eric Schmitt declined to be considered for Attorney General. On November 12, John Paulson declined to be considered for Secretary of the Treasury, and it was announced that Donald Trump Jr. would not be joining the administration.

In July 2024, Trump selected Ohio U.S. Senator JD Vance as his running mate at that year's Republican National Convention. Vance was supported by Donald Trump Jr., Elon Musk, and Tucker Carlson and bolstered by a series of media events, including a contentious primary debate with Josh Mandel and Mike Gibbons, an affirmation of his support for Trump in The Wall Street Journal as Ron DeSantis advanced in conservative media, and a cooperative visit to East Palestine, Ohio, following a train derailment in February 2023.

On November 10, Trump announced that former acting Immigration and Customs Enforcement director Tom Homan will serve as "border czar". The following day, CNN reported that Stephen Miller will serve as Trump's deputy chief of staff for policy. The day after, Trump announced former Cabinet Secretary Bill McGinley would serve as his next White House Counsel; real estate investor Steve Witkoff would serve as the president's special envoy to the Middle East. Later that day, Mediaite and The Independent reported that Trump's personal lawyer Alina Habba was his top contender for White House Press Secretary; Fox News later reported that she had declined. The Wall Street Journal reported on November 13 that Trump wanted first-term Trade Representative Robert Lighthizer to serve as his "trade czar".

Robert F. Kennedy Jr., who ran against Trump but withdrew his nomination, has privately discussed having a senior health role in Trump's second presidency. Kennedy stated that Trump "asked [him] to clean up corruption and conflicts at the agencies and to end the chronic disease epidemic" in an interview with The Washington Post in October 2024. On November 12, Trump announced that Elon Musk and Vivek Ramaswamy would advise a new Department of Government Efficiency.

NBC News reported on November 11 that Federal Bureau of Investigation director Christopher A. Wray is preparing for a forced exit. The next day, Trump announced that he would nominate former Arkansas Governor Mike Huckabee as Ambassador to Israel. Trump was reported to be seriously considering nominating personal lawyer Todd Blanche as United States Deputy Attorney General, which he went through with two days later, along with nominating personal lawyers Emil Bove as associate deputy attorney general and D. John Sauer as Solicitor General. On November 15, The Wall Street Journal reported that Trump was considering Fox Business host and former director of the National Economic Council Larry Kudlow for a "senior economic role",, but Kudlow subsequently declined to serve in such a role. That same day, Trump announced that Steven Cheung, Sergio Gor and Karoline Leavitt would serve as White House communications director, personnel director and Press Secretary, respectively. Also on the 15th, it was reported that former congressman Mike Rogers was being considered for FBI director.

Trump declared that abortion should be delegated to states in April 2024. To that extent, he stated that in a Time interview he would allow states to monitor pregnancies and criminally charge abortion patients. Trump criticized the Arizona Supreme Court's ruling in Planned Parenthood Arizona v. Mayes (2024), in which the court upheld an 1864 law criminalizing abortions except to save the life of the mother, stating that he would not sign a federal abortion ban and reaffirmed his position in October.

After the Alabama Supreme Court ruled in LePage v. Center for Reproductive Medicine (2024) that frozen embryos are living beings, Trump positioned himself in favor of in vitro fertilisation.

Trump's transition team for climate and the environment is led by David Bernhardt, a former oil lobbyist who served as interior secretary, and Andrew R. Wheeler, a former coal lobbyist who led the Environmental Protection Agency under Trump. The team is preparing to withdraw from the Paris Agreement for a second time, expand drilling and mining on public land, and dismantle offices working to end pollution, while other officials have discussed moving the Environmental Protection Agency from Washington, D.C. Trump will redraw the boundaries of the Bears Ears and Grand Staircase–Escalante National Monuments as he did in his first presidency, end a pause on new natural gas export terminals that began under president Joe Biden, and prevent states from setting their own pollution standards.

At a private dinner at Mar-a-Lago in April 2024, Trump promised fossil fuel companies that he would roll back environmental regulations if they donated to his campaign.

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Trump has promised to impose higher tariffs on imports from all countries, particularly China.

During his first term, Trump cut funding to the Department of Education, while continuing to criticize it. During his 2024 campaign, Trump actively promoted the idea of abolishing the Department of Education and proposed handing over control of education to individual state governments.

Elon Musk and Vivek Ramaswamy will lead the Department of Government Efficiency, a commission that would "provide advice and guidance from outside of government".

On November 14 at a speech at Mar-a-Lago, Florida, Trump announced that he would nominate Robert F Kennedy Jr for the position of health secretary. This appointment caused controversy, due to Kennedy's repeated endorsement of anti-vaccine conspiracy theories, with the director of the American Public Health Association stating that Kennedy "already caused great damage in health in the country" and that he is also "a person without a health background".

Trump intends to expand and revive immigration policies he imposed during his first presidency, including his travel ban on Muslims, expel asylum seekers by asserting that they carry infectious diseases, deputize police officers and soldiers to assist Immigration and Customs Enforcement in mass deportations, and establish sprawling detention camps, according to The New York Times. After his win, Trump said "there is no price tag" to carry out these deportations.

Trump announced on November 10, 2024 that Tom Homan will be joining the incoming administration as the "border czar", writing that "Homan will be in charge of all deportation of illegal aliens back to their country of origin."

In his second campaign, Donald Trump has detailed a range of proposals aimed at reversing recent LGBT-related policies and reshaping federal guidelines on gender identity and transgender rights. Trump has stated that on "day one," he would reverse the Biden administration’s Title IX expansion, which protects transgender students' rights to use bathrooms, locker rooms, and pronouns that align with their gender identity. Trump also pledged to cut federal funding to schools promoting "critical race theory, transgender insanity, and other inappropriate racial, sexual, or political content."

His proposed policies would significantly limit gender-affirming care, including calling for a federal ban on such care for minors and blocking Medicare and Medicaid funding for doctors providing gender-affirming services. Trump has also proposed forbidding federal agencies from "promoting" gender transition and plans to task the Justice Department with investigating potential long-term effects of gender-affirming treatments.

In a September 2024 Truth Social post, Trump stated that "... those people that cheated will be prosecuted to the fullest extent of the Law ..." in reference to the 2024 election. In his 2024 book Save America, Trump threatened life imprisonment for Meta Platforms chief executive Mark Zuckerberg if he does anything illegal.

Trump is expected to end the Department of Justice's prosecutions against him in Washington, D.C. and Florida. Special counsel Jack Smith is considering ending his prosecutions early and submitting a final report to Attorney General Merrick Garland before Trump is inaugurated, according to The Washington Post.

Trump has said multiple times that if he were reelected in 2024, he would pardon rioters of the January 6 Capitol attack. As of March 2024, 500 people had been sentenced to prison terms and 1,358 had been criminally charged.

In May 2024, Trump said that he would commute Ross Ulbricht's sentence on his first day in office. Ulbricht is serving a life sentence for creating and operating the darknet market website Silk Road, which operated as a hidden service on the Tor network and facilitated the sale of narcotics and other illegal products and services. Trump has also floated or hinted at issuing potential pardons for Julian Assange, Hunter Biden, and Peter Navarro; media outlets have also speculated that Trump may issue pardons for Eric Adams and Todd and Julie Chrisley.

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Following his victory, Trump called Russian president Vladimir Putin to warn him not to escalate the Russo-Ukrainian War, expressing an interest in resolving the war at a later date.

On November 14, 2024, Argentine president Javier Milei headed to Florida to meet with Trump at Mar-a-Lago. He was the first foreign head of state to travel to the United States after Trump's victory and to meet the president-elect. A right-wing libertarian economist, Milei had previously shown his fervent support for Donald Trump and his politics, wanting to strengthen diplomatic and economic ties between Argentina and the Western world. In a call following the election results, Trump called Milei his "favorite president" in response according to reports. The president of Argentina gave a speech at a CPAC summit in Miami. Milei also met with Department of Government Efficiency planned-directors Elon Musk and Vivek Ramaswamy to advise them on their goal to "dismantle bureaucracy", cut government spending and reorganize the federal personnel.

Farnaz Fasihi or New York Times reported of positive talks between Elon Musk and Ambassador to UN Amir Saeid Iravani in a secret location.

Before taking office, Trump urged Israeli prime minister Benjamin Netanyahu to end the war in Gaza within two months and opened the door to attacks on Iran's nuclear facilities. Following the election, Trump spoke with Palestinian President Mahmoud Abbas for the first time since 2017. During their phone call, Trump expressed his desire to quickly end the war in Gaza.

Trump has numerously stated that he, as the president, would not commit to defending NATO member states that are not spending at least 2% of their GDP on defense. Additionally, Vice President-Elect JD Vance has stated that in his view NATO is a "welfare client" and that it should be "a real alliance".