Shwebo District is a district in south-central Sagaing Division of Burma (Myanmar). Its administrative center is the city of Shwebo.

The district consists of the following townships:

• Khin-U Township
• Shwebo Township
• Wetlet Township
• Taze Township
• Ye-U Township
• Tabayin Township (formerly from Monywa District)

Shwebo District also consisted of the following townships, which formed to become Kanbalu District:

• Kanbalu Township
• Kyunhla Township

The area is supported by rice farming, fisheries and timbering.

23°12′N 95°31′E / 23.200°N 95.517°E / 23.200; 95.517