Siernicze Wielkie [ɕɛrˈnit͡ʂɛ ˈvjɛlkʲɛ] is a village in the administrative district of Gmina Ostrowite, within Słupca County, Greater Poland Voivodeship, in west-central Poland. It lies approximately 17 kilometres (11 mi) north-east of Słupca and 75 km (47 mi) east of the regional capital Poznań.