Sint-Niklaas railway station (Dutch: Station Sint-Niklaas; French: Gare de Saint-Nicolas) is a railway station in Sint-Niklaas, East Flanders, Belgium. The original station opened on 3 November 1844 on railway line 59. The current station was built in 1972 by the architects Ludwig Van Wilder and Omer De Grootte. The train services are operated by the National Railway Company of Belgium (NMBS/SNCB).

The following services currently serve the station:

• Intercity services (IC-02) Ostend - Bruges - Ghent - Sint-Niklaas - Antwerpen
• Intercity services (IC-04) Lille/Poperinge - Kortrijk - Ghent - Sint-Niklaas - Antwerp
• Intercity services (IC-26) Kortrijk - Tournai - Halle - Brussels - Dendermonde - Lokeren - Sint Niklaas (weekdays)
• Intercity services (IC-28) Ghent - Sint-Niklaas - Antwerp (weekdays)
• Local services (L-20) Sint-Niklaas – Mechelen – Leuven (weekdays)
• Local services (L-27) Sint-Niklaas - Mechelen (weekends)
• Local services (L-30) Lokeren - Sint-Niklaas - Antwerp

Preceding station	NMBS/SNCB			Following station
Lokeren towards Oostende		IC 02		Beveren towards Antwerpen-Centraal
Lokeren towards Lille-Flandres or Poperinge		IC 04		Antwerpen-Berchem towards Antwerpen-Centraal
Belsele towards Kortrijk		IC 26 weekdays		Terminus
Lokeren towards De Panne		IC 28 weekdays		Antwerpen-Zuid towards Antwerpen-Centraal
Terminus		L 20 weekdays		Temse towards Leuven
		L 27 weekends		Temse towards Mechelen
Belsele towards Lokeren		L 30		Nieuwkerken-Waas towards Antwerpen-Centraal

• 
  Frontal view
• 
  View of the platforms and tracks
• 
  Place name sign on a platform

• List of railway stations in Belgium
• Rail transport in Belgium

• Belgian Railways website for Sint-Niklaas