The Sousa River (Portuguese: rio Sousa, pronounced [ˈsozɐ]) is a river in Portugal, a tributary of the Douro. It rises in the parish of Friande, Felgueiras, in the Porto District of northwest Portugal, and is a right tributary of the Douro, which it meets at the parish of Foz do Sousa, Gondomar, about 16 km from the mouth of the Douro.

The name is from Latin Saxa 'rocks', later called Sausa.

• Ferreira River
• Cavalum River
• Messio River

41°05′16″N 8°31′13″W / 41.08776°N 8.52023°W / 41.08776; -8.52023