The South Campus Historic District is a historic district in Chico, California which was named to the National Register of Historic Places in 1991 through efforts of the Chico Heritage Association. The district is situated entirely within the South Campus Neighborhood. The historical district extends from Salem Street to Cherry Street, and from West Second Street to West Sixth Street. Whereas, the neighborhood extends from West Second Street south to West Ninth Street and west from Salem Street all the way to the city limits, which, in that area, is called the "Green Line." The South Campus Neighborhood Association represents the interests of the neighborhood to the community. There are several fraternity and sorority houses in the area, and the city has designated the South Campus Fraternity/Sorority Overlay Zone which is largely contiguous with the neighborhood and district.

Historically, this area was the first residential area established in the city. The area was surveyed for laying out streets in 1860. South Campus is home of the Stansbury House, the Southern Pacific Depot, and the Language Houses.

Currently, South Campus is a dynamic residential neighborhood consisting overwhelmingly of young renters under thirty-five, and specifically Chico State students. It is one of the most densely populated areas of the city. The intersection of Fifth and Ivy Streets is a neighborhood commercial core referred to locally as "Five and I".

The historic district consists of 114 individual buildings which have been named in the register as contributing to the historical district. They include:

• The Language Houses consist of six houses on West Third Street which had previously been owned by Chico State University's Department of Foreign Languages and Literatures. The houses had been used as student housing with each house having a language theme. The houses had fallen into disrepair under university management of the properties, and the sale of the properties to a developer interested in restoring the historical nature of the houses was a drawn out matter requiring the intervention of the state legislature. Today the houses are privately owned, have been restored and are occupied student housing. The Language Houses are named:

• H.W. Crew House (also called the Spanish House and Alpha Phi House)
• Rouke-Halle House (also called the German House)
• C.C. Richardson House (also called the Italian House)
• J.V. Richardson House
• Charles Ball House (also called the International House)
• French House (also called the Kappa Sigma Delta House)

In September 1996, a group of residents, property owners, business owners, and student organization representatives got together to form the South Campus Neighborhood Association. This was, in part a result of the City Council, in May of that year, directing the Planning Commission to study zoning for "Student Living Groups" (i.e. fraternities and sororities, etc.). The group prepared a Constitution for the neighborhood association, and an outline for a neighborhood plan; both of which were presented at a neighborhood meeting in March 1997.

The association has successfully lobbied the city for increased lighting, infrastructure repairs (such as sidewalks), increased community involvement in police strategies, and amendments to the city's noise ordinance. The neighborhood association requested that the city consider creating a Special Events Permit, so as to address some of the issues arising from the youth of its residents. Although the city, did not establish such a permit, the proposed zone which was to be associated with this permit eventually was approved by the council as a unique Fraternity/Sorority Overlay Zone.

The land use regulations in the zone are combined with those of the base district, except that fraternities and sororities shall be a permitted use, with the approval of a ministerial permit by the Planning Director.