The South Fork Humboldt River is a river in Elko County, Nevada, United States.

The river originates in a fan-shaped group of canyons draining the western slopes of the Ruby Mountains in northeastern Nevada. These headwaters run from Ruby Dome south to King Peak and include Echo, Box, Kleckner, North Furlong, Long, Segunda, Drown, and Rattlesnake Canyons. Streams draining these canyons exit the mountains and converge at an elevation of 5,775 feet (1,760 m), near the town of Lee and within the tribal lands of the Te-Moak tribe of the South Fork Band of the Western Shoshone.

Continuing its northwest course, the river merges with the flow of Huntington Creek, passes through the historic area of Twin Bridges, and then enters the more recent South Fork Reservoir, State Park, and South Fork Dam dating from 1988. It then passes through South Fork Canyon, which merges with Tenmile and Dixie creeks' flows. It was here that, on September 25, 1846, the Donner Party wagon train completed the segment of their journey on the Hastings Cutoff, and rejoined the original California Trail.

After an estimated total of 38 miles (61 km), the South Fork flows into the main branch of the Humboldt River at approximately 40°46.3′N 115°53.3′W / 40.7717°N 115.8883°W / 40.7717; -115.8883 and at an elevation of 4,998 feet (1,523 m), about 7 miles (11 km) southwest of the city of Elko.

• List of rivers in Nevada

Media related to South Fork Humboldt River at Wikimedia Commons