South Uptown is a residential neighborhood in the Calhoun Isles community of Minneapolis, Minnesota.

In 2018, the neighborhood voted to change its name to South Uptown from its former name, Calhoun Area Residents' Action Group (CARAG) after its namesake, the former Lake Calhoun, was renamed to Bde Maka Ska. Other potential names for the neighborhood included "Bryant Park" and "Bryant Square". The Minneapolis City Council approved the name change in November 2018.

It is located directly south of Lowry Hill East and directly east of East Bde Maka Ska. Its boundaries are Lake Street to the north, Lyndale Avenue to the east, 36th Street to the south, and Hennepin Avenue to the west. South Uptown, Lowry Hill East, East Bde Maka Ska and East Isles form the business district of Uptown.

It is in Ward 10, represented by council member Aisha Chughtai.