The Cathedral of Saint John in Chiayi, also known as St. John's Cathedral (traditional Chinese: 聖若望主教座堂; simplified Chinese: 圣若望主教座堂; pinyin: Shèngruò Wàngzhǔjiào Zuòtáng) is the cathedral church of the Roman Catholic Diocese of Chiayi. It is located at 62nd Street Minchuan, East District, Chiayi City, Taiwan.

It is the mother church for Roman Rite worshipers in the diocese of Chiayi, also written Kiayi or (Dioecesis Kiayiensis; 天主教嘉義教區) which was raised to its current status in 1962 by the bull Cum Apostolica by Pope John XXIII. It is under the pastoral responsibility of Bishop Thomas Chung An-zu.

The current cathedral was built between 1957 and 1958. It has been renovated several times especially after the 1964 Baihe earthquake, after by several floods and typhoons, and a small fire that occurred in 1997.

• Chinese Rites Controversy
• Catholic Church in Taiwan

23°29′03″N 120°27′40″E / 23.4842°N 120.4611°E / 23.4842; 120.4611