St. Nicholas Antiochian Orthodox Cathedral is a cathedral church of the Greek Orthodox Patriarchate of Antioch in New York City and the seat of the primate of the Antiochian Orthodox Christian Archdiocese of North America. First established in Lower Manhattan, it is now located in Brooklyn.

The first chapel was established in 1895, by Saint Raphael of Brooklyn at a location on Washington Street in Little Syria, Manhattan. He founded the Syrian Orthodox congregation and then moved it to Brooklyn's Pacific Street in 1902. In 1920, the congregation relocated to a building built in 1870 that was formerly an Episcopal church at 355 State Street in Boerum Hill, Brooklyn.

• Antiochian Greek Christians

• Official website