St. Mark's Church is an Anglican parish church in Grenoside, South Yorkshire, England. It is in the Deanery of Ecclesfield, and was built in 1884.

Regular Sunday services are at 10:00am. Hospitality, fellowship and food are a speciality; first Sunday of each month breakfast is served to all-comers from 9.45am. Other groups for adults and children meet at different times through the week.

St Mark's is a venue for Christian weddings, funerals and baptisms.

The church has two Focal Ministers, part-time volunteers who are authorised to lead and serve in the parish. They are Readers (Licensed lay ministers). The Oversight Minister and Priest-in-charge is the Vicar of Ecclesfield.