Stražisko is a municipality and village in Prostějov District in the Olomouc Region of the Czech Republic. It has about 400 inhabitants.

Stražisko consists of three municipal parts (in brackets population according to the 2021 census):

• Stražisko (157)
• Maleny (117)
• Růžov (143)

Stražisko is located about 14 kilometres (9 mi) northwest of Prostějov and 23 km (14 mi) west of Olomouc. It lies on the border between the Drahany Highlands and Zábřeh Highlands. The highest point is at 464 m (1,522 ft) above sea level. The Romže River flows through the municipality.

The first written mention of Stražisko is from 1379. The early history of the village was connected with the Grünberg Castle, located on a hill above the village. In the 16th century, the castle was abandoned and fell into disrepair. In 1722, the ruin was demolished and a church was built on the site.

Historical population

Year Pop. ±% 1869 682 —     1880 697 +2.2% 1890 710 +1.9% 1900 673 −5.2% 1910 729 +8.3%	Year Pop. ±% 1921 753 +3.3% 1930 756 +0.4% 1950 662 −12.4% 1961 664 +0.3% 1970 602 −9.3%	Year Pop. ±% 1980 499 −17.1% 1991 416 −16.6% 2001 424 +1.9% 2011 414 −2.4% 2021 417 +0.7%
Source: Censuses

Stražisko is located on the railway line Prostějov–Dzbel.

The main landmark of Stražisko is the Church of the Guardian Angels, located on a hill inside the built-up area. It was built in the Baroque style in 1728. The path to the church is lined with 14 Stations of the Cross, dating from 1854.

• Otto Wichterle (1913–1998), chemist, inventor of contact lens; lived and died here
• Jan Hrbatý (1942–2019), ice hockey player

• Official website