Svatobořice-Mistřín is a municipality in Hodonín District in the South Moravian Region of the Czech Republic. It has about 3,500 inhabitants.

The municipality is made up of the villages of Svatobořice and Mistřín.

Svatobořice-Mistřín is located about 13 kilometres (8 mi) north of Hodonín and 41 km (25 mi) southeast of Brno. It lies in the Kyjov Hills. The highest point is the hill Záviště at 256 m (840 ft) above sea level. The Kyjovka River flows through the municipality.

The first written mention of Mistřín is in a deed of King Ottokar I of Bohemia from 1228. Svatobořice was first mentioned in 1349, however it is probably older than Mistřín. The two formerly separate municipalities merged in 1964.

Historical population

Year Pop. ±% 1869 1,724 —     1880 1,861 +7.9% 1890 1,969 +5.8% 1900 2,337 +18.7% 1910 2,686 +14.9%	Year Pop. ±% 1921 2,964 +10.3% 1930 3,823 +29.0% 1950 3,069 −19.7% 1961 3,521 +14.7% 1970 3,593 +2.0%	Year Pop. ±% 1980 3,646 +1.5% 1991 3,486 −4.4% 2001 3,483 −0.1% 2011 3,419 −1.8% 2021 3,394 −0.7%
Source: Censuses

Svatobořice-Mistřín is known for viticulture. The municipality lies in the Slovácká wine sub-region.

There are no railways or major roads passing through the municipality.

The main landmark of Mistřín is the Church of the Visitation of the Virgin Mary. The construction of the Baroque church began in 1744 and was finished in 1769–1771, when the cemetery was established. It replaced an old Romanesque church.

In Svatobořice is the Svatobořice Castle. It was built after 1570, during the rule of the Morkovsky of Zástřizly family. The Kurucs burned the castle down in 1705, but it was rebuilt by the Serényi family. Today it is privately owned and inaccessible.

• Vladimír Vašíček (1919–2003), painter

• Official website