Tafalofefe Hospital is a provincial government funded hospital in the Mnquma Local Municipality area outside Butterworth, Eastern Cape in South Africa.

The hospital includes an emergency department, ophthalmology, outpatients department, surgical services, medical services, operating theatre & CSSD services, pharmacy, anti-retroviral (ARV) treatment for HIV/AIDS, post-trauma counseling services, NHLS laboratory, laundry services, kitchen services and mortuary.

• Eastern Cape Department of Health website - Amathole District hospitals