Tak Oi Secondary School (Chinese: 德愛中學), commonly abbreviated as TOSS, is a girls' secondary school situated in Tsz Wan Shan, Wong Tai Sin, Hong Kong. It was established in 1970 by the Missionary Sisters of the Immaculate Conception (MIC).

The school was named "Tak Oi" (meaning charity) to complete the theological virtues of Faith, Hope, and Love; the former two of which are the names of the other MIC schools in Hong Kong (Tak Sun School [zh] and Good Hope School).

The school uses English as the medium of instruction for all subjects except Chinese language, Putonghua, Chinese history, and ethics & religious education.

The school was founded in 1970 in response to the needs of the Hong Kong society and the request of Catholic bishop Lawrence Bianchi. At that time, the government was developing the area of Tsz Wan Shan, a district near Wong Tai Sin in East Kowloon. The official opening of the school and the unveiling of a commemorative plaque was officiated by Director of Education John Canning [zh] in 1971.