The Tarapacá Region (Spanish: Región de Tarapacá, pronounced [taɾapaˈka]) is one of Chile's 16 first-order administrative divisions. It comprises two provinces, Iquique and Tamarugal. It borders the Chilean Arica y Parinacota Region to the north, Bolivia's Oruro Department and Potosí Department on the east, Chile's Antofagasta Region to the south and the Pacific Ocean to the west. The port city of Iquique is the region's capital.

Much of the region was once the Tarapacá Province of Peru, which was annexed by Chile under the 1883 Treaty of Ancón at the close of the War of the Pacific. The region was important economically as a site of intense saltpeter mining, before synthetic nitrate manufacturing became possible. A number of abandoned mining towns can still be found in the region.

The present day Tarapacá Region was created in 2007 by subdividing the former Tarapacá Region under Law No. 20,175, which was signed by President Michelle Bachelet in Arica.

The government of the region resides in the intendant, who is assigned by the president. Each of the region's two provinces are further subdivided into communes.

Province	Capital	Commune	Other towns
Iquique	Iquique	Iquique
		Alto Hospicio
Tamarugal	Pozo Almonte
		Huara	Pisagua
		Camiña
		Colchane
		Pica
		Pozo Almonte	Mamiña

A desert climate dominates the region. Near the coast, cloudiness can limit the temperature swing throughout the day, but in other drier areas, temperatures can vary greatly as is typical in deserts. A marginal desert region can be found over 3,000 m (9,843 ft) above sea level, which sees milder temperatures and summer rains.

• Isluga River
• Cariquima
• Concosa (Altiplano)

• Fishing
• Tourism
• Mining
  • Cerro Colorado
  • Collahuasi

• 2007 Tocopilla earthquake
• Coastal Cliff of northern Chile
• Pulpería

• Gobierno Regional de Tarapacá Official website (in Spanish)
• Visita Tarapacá Web platform with useful information about the Tarapacá region (in Spanish and English)