Telangana Secretariat, officially known as Dr. B. R. Ambedkar Telangana State Secretariat situated at Hyderabad, is the administrative office of the employees of the Government of Telangana in India. The Telangana government on 15 September 2022 has decided to name the new Secretariat complex as Dr. B. R. Ambedkar Telangana Secretariat. Designed by Chennai-based Architects Ponni Concessao and Oscar Concessao, the complex has been built by Shapoorji Pallonji and Company Pvt Limited with all Green Building Council norms. There is a 125-ft tall statue of Ambedkar beside the Telangana Secretariat.

The old secretariat had an old Nizam period heritage structure called as Peshi or G-block. It had 10 blocks and spread over 25.5 acres (10.3 ha). After the bifurcation of Andhra Pradesh to form the new state of Telangana, the building were divided into 58:42 for Andhra Pradesh and Telangana for 10 years, until 2024.

The razing of old Secretariat complex of Telangana began in Hyderabad early in July 2020, with the government starting demolition of the old buildings and paving the way for construction of a state-of-the-art new complex in its place. Built in Indo-Saracenic style, the new Telangana Secretariat also blends the Indo-Islamic architectural features generally with domes.

The secretariat has various following departments based on the rules of business, from which the business of state governance is transacted. The official head of the each department is the secretary to government.