State Route 298 (SR 298), also known as Genesis Road, is a north–south state highway in the Cumberland Plateau region of East Tennessee.

SR 298 begins in Cumberland County in Crossville at an intersection with US 127/SR 28 just north of downtown. It goes northeast as a two-lane highway through neighborhoods before widening to a four-lane undivided highway and passing through industrial areas, where it crosses over the Little Obed River. SR 298 then has an interchange with I-40 (exit 320) before leaving Crossville and narrowing to two lanes. The highway then winds it way northeast through farmland before crossing the Obed River and entering the Catoosa Wildlife Management Area. SR 298 passes through the wooded areas of the management area as it crosses into Morgan County. The highway then passes through rural areas and farmland as it leaves the Catoosa Wildlife Management Area. SR 298 continues east to cross a bridge over Clear Creek shortly before coming to an end at an intersection with SR 62 west of Lancing.

County	Location	mi	km	Destinations	Notes
Cumberland	Crossville	0.0	0.0	US 127 (North Main Street, SR 28) – Jamestown, Downtown, Pikeville	Southern terminus
				Bridge over the Little Obed River
				SR 462 west (Interstate Drive)	Eastern terminus of TN-462
				I-40 – Nashville, Knoxville	I-40 exit 320
	​			Bridge over the Obed River
Morgan	​			Bridge over Clear Creek
	​	25.8	41.5	SR 62 (Nashville Highway) – Clarkrange, Lancing, Wartburg	Northern terminus
1.000 mi = 1.609 km; 1.000 km = 0.621 mi