Three Wells Fargo Center is a 450-foot (137 m) high rise in Charlotte, North Carolina. Completed in 2000, the building consists of 32 floors with 890,000 square feet (83,000 m) of office space; it also includes an underground parking garage, an attached 10-story low-rise known as the Ratcliffe on the Green, and connects to Two Wells Fargo Center via skybridge, as part of the Overstreet Mall.

Prior to the First Union-Wachovia merger, this building was called Three First Union Center. In December 2010, as a result of Wells Fargo's 2008 purchase of Wachovia, the building was renamed from Three Wachovia Center to Three Wells Fargo Center.

A branch of the Wells Fargo History Museum was located in the building, until all but one of the bank's thirteen museums were closed to align with corporate strategy. The museum's exhibits included gold mining in North Carolina, a 19th-century stagecoach, and a model of an 1889 Wachovia Bank branch from Winston-Salem. In 2022, the facility the museum was housed at was donated to the Levine Museum of the New South.

• List of tallest buildings in Charlotte
• List of tallest buildings in North Carolina
• One Wells Fargo Center
• Two Wells Fargo Center

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