Tirstrup is a town in East Jutland, Denmark. As of 1 January 2024, the town has a population of 442.

Tirstrup is located 44 kilometers from Aarhus and 18 kilometers from Grenaa. The town is a home to Aarhus Airport. Tirstrup lies in the Syddjurs Municipality and is governed as part of the Central Denmark Region (Region Midtjylland).