Tonoloway Creek, also known as Great Tonoloway Creek, is a 31.4-mile-long (50.5 km) tributary stream of the Potomac River in the U.S. states of Maryland and Pennsylvania.

Tonoloway Creek empties into the Potomac River at Hancock, Maryland.

Tributaries

(travelling upstream)

• Little Tonoloway Creek, approximately 5.5 miles (8.9 km) upstream of the Potomac River

See also

• List of Maryland rivers
• List of rivers of Pennsylvania